pentobarbital will lower the level or influence of itraconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.
pentobarbital will decrease the extent or impact of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.
pentobarbital will reduce the level or impact of estrogens conjugated artificial by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the level or outcome of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Loss of, or reduced reaction to tofacitinib may perhaps take place when coadministered with strong CYP3A4 inducers
pentobarbital raises results of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Caution/Observe. Coadministration of ifosfamide with CYP2B6 inducers could maximize metabolism of ifosfamide to its metabolite. Check for amplified effects/toxicities if coupled with CYP2B6 inducers.
pentobarbital decreases levels of vandetanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with strong CYP3A4 inducers; these medicine lessen exposure to vandetanib by around 40%.
Research in laboratory animals have proven that barbiturates cause reduction from the tone and contractility from the uterus, ureters, and urinary bladder. On the other hand, concentrations of the medications necessary to develop this influence in human beings are usually not arrived at with sedative-hypnotic doses.
pentobarbital will reduce the extent or effect of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lessen the extent or result of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
This helps make overdose a great deal more possible; therefore, combining central nervous method depressant medications is extremely unsafe.
pentobarbital will lower the extent or effect of here hydrocortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the level or result of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or outcome of elagolix by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Abrupt withdrawal of antiseizure drugs might maximize seizure frequency, withdraw pentobarbital step by step.